Antibody-conjugated Lead Scientist

Responsibilities:

1. Be responsible for the development of coupling technology, including the design of coupling reactions, process development, characterization, analysis and purification.

2. Collaborate within the team to enrich the coupling platform technology and support the coupling needs of various internal coupling drugs.

3. Based on professional knowledge and experience, provide technical support to the team and guide project members to complete related experimental work.

4. Be responsible for the process development, parameter screening and optimization of LNP formulations (especially based on microfluidic technology), to improve encapsulation rate, stability and reproducibility.

5. Solve technical problems encountered during process development and pilot-scale expansion.

Requirements:

1. Relevant majors such as organic chemistry, medicinal chemistry, chemical biology, biopharmaceuticals, pharmacy, biochemistry, etc., with a doctoral degree.

2. Have no less than 1 year of experience in large molecule coupling.

3. Proficient in protein and other large molecule coupling experimental skills (reaction condition optimization, purification, characterization and quality control).

4. Familiar with the development process of coupling drugs and able to collaborate efficiently with the large molecule, analysis and other teams.

5. Have innovative thinking and the ability to solve problems actively, be able to continuously track the latest progress in coupling technology, and independently promote internal R&D projects of the team.